منابع مشابه
Editorial: Dendritic spines: from shape to function†
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متن کاملLearning by geometrical shape changes of dendritic spines
The role of dendritic spines in neuronal information processing is still not completely clear. However, it is known that spines can change shape rapidly during development and during learning and these morphological changes might be relevant for information storage (memory formation). We demonstrate the impact of shape variations on electrical signal propagation via dendritic spines using a bio...
متن کاملPeriodic F-actin structures shape the neck of dendritic spines
Most of the excitatory synapses on principal neurons of the forebrain are located on specialized structures called dendritic spines. Their morphology, comprising a spine head connected to the dendritic branch via a thin neck, provides biochemical and electrical compartmentalization during signal transmission. Spine shape is defined and tightly controlled by the organization of the actin cytoske...
متن کاملDendritic Spines
Dendritic spines are important sites of excitatory synaptic transmission and changes in the strength of these synapses are likely to underlie important higher brain functions such as learning and memory. Spines form biochemical compartments for isolating reactions that occur at one synapse from those at other synapses thereby providing a possible way to ensure the specificity of connections bet...
متن کاملDendritic Spines
What are they? Dendritic spines are small protrusions that emerge from the dendrites of neurons (Figure 1). Most excitatory synapses in the brain are found on spine heads. Typically, a spine consists of a bulbous head, volume 0.001–1 μm3, at the end of a thin spine neck, diameter around 0.1 μm. A 100 μm length dendrite can contain several hundred spines. The human cerebral cortex is thought to ...
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ژورنال
عنوان ژورنال: Nature Reviews Neuroscience
سال: 2005
ISSN: 1471-003X,1471-0048
DOI: 10.1038/nrn1711